For a wide range of small organic molecules tetraarlyadamantane derivatives can chaperone the formation of high quality cocrystals suitable for absolute structure determination. The method is easy-to-use and has a high success rate in the 95% range.
Initial studies indicate that TBro works best for analytes with a molecular weight between 150 and 270 D and a calculated lipophilicity (logP) between 3.5 and 6.
The set consists of:
- 20 mg 1,3,5,7-Tetrakis(2-bromo-4 methoxyphenyl)adamantane (TBro) C38 H36 Br4 O4
- 30 crystallization vials
- Instruction set on memory stick