MALDI AnchorChip Targets

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Patented AnchorChip™ targets are polished steel targets with hydrophilic sample and calibrant spots surrounded by a hydrophobic barrier for MALDI sample preparation. Sample positions on contain "anchors"; hydrophilic patches surrounded by a hydrophobic ring. The "anchor" localizes droplets at the sample position and the hydrophobic ring prevents sample spreading and concentrates the sample into a spot between 0.4 and 2 mm in diameter. The localization effect ensures that every single laser shot fired throughout an automatic run will hit a sample spot. This significantly increases the efficiency of the MALDI acquisition process.

Compatible with autofleX series, ultrafleXtreme, rapifleX series, and neofleX series, also compatible with Dual ESI/MALDI Sources of timsTOF fleX, scimaX and solariX series instruments.

The MTP target frame III (Part No. 8074115) is required to mount MTP targets in Bruker MALDI ion sources.

Examples of application

• Automated High-Throughput Oligo QC: From Automated Sample Preparation to MALDI Spectra Assessment
• Automated High-Throughput Clone Screening of Therapeutic Antibodies
• Extensive LC-Top-Down MS Sequence Confirmation of the NISTmAb Reference Material 8671
• Kinase inhibition screening by label-free mass spectrometry employing the MALDI PharmaPulse HTS solution
• Biomarker Identification in Large Clinical Sample Sets