SPR His-Tag Capture Sensor
Description
The His-Tag Capture Sensor is based on a polycarboxylate hydrogel functionalized with tris-NTA moieties to capture poly-His-tagged molecules through metal chelation. Compared to a mono-NTA-based sensor, the tris-NTA sensor features improved affinity towards a His-tag resulting in reduced loss of captured target proteins. The sensor can be used for interaction studies of small to large analytes.
It is recommended to use the His-Tag Capture Sensors with the His-Tag Capture Reagent Kit containing NiSO4 activation and EDTA regeneration solutions.
Attention! Our product 1862618 – His-Tag Capture Sensor (12 pk.) is retired. The sensor chips are still available. Please order 1814896 – His-Tag Capture Sensor (1 pk.) instead.
Application
- Capture of poly-His-tagged molecules
Compatibilities
Sierra SPR-24 Pro and Sierra SPR-32 Pro
Additionally Available
Technical Data
- Matrix: Polycarboxylate hydrogel
- Further Modification: Pre-immobilized poly-NTA
- Sensor Regeneration: EDTA

