Biotin-Tag Capture Sensor
Bruker Daltonics SPR
Part No:1862619
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The Biotin-Tag Capture Sensor is based on a polycarboxylate hydrogel sensor with pre-immobilized Streptavidin on the surface. It is suitable to capture biotinylated ligands, mainly peptides, proteins, and DNA. The non-covalent interaction between biotin and streptavidin forms quickly and has a high affinity (KD = 10-15 M). Thus, it provides a stable immobilization level for capture-based assays and makes the sensor an alternative for ligands that are difficult to immobilize covalently.
As the streptavidin – biotin binding is unaffected by extremes of temperature, organic solvents, pH, and most denaturing agents, the interaction between analyte and ligand can be disrupted even under harsh regeneration conditions without a loss of reproducibility.
Attention! Our products 1862620 – Biotin-Tag Capture Sensor (3 pk.) and 1862621 – Biotin-Tag Capture Sensor (12 pk.) are retired. The sensor chips are still available. Please order 1862619 – Biotin-Tag Capture Sensor (1 pk.) instead.
- Capture of biotin-tagged molecules
Sierra SPR-24 Pro and Sierra SPR-32 Pro
- Matrix: Polycarboxylate hydrogel
- Modification: Pre-immobilized Streptavidin
